MBI (Michigan Biotechnology Institute)

Founded in 1981, MBI is a wholly owned 501(c)(3) subsidiary of the Michigan State University Foundation.

For many years, MBI worked with industry partners to provide unique derisking capabilities while driving the commercialization of proprietary biobased technologies — specifically technologies related to fumaric acid, succinic acid and the AFEX platform — all of which is available for licensing.

Fumaric Acid

Fumaric acid has been widely used as a food additive and is recognized as a versatile intermediate for the production of bio-based polymers. Fumaric acid can potentially replace maleic anhydride in various applications.  MBI has developed a patented fermentation and recovery process for biobased fumaric acid.

MBI is actively seeking to license or sell its patents for its biobased succinic acid platform.

Succinic Acid

Succinic acid has been widely recognized as a versatile intermediate for the production of solvents, chemicals, and materials that can displace current petrochemical feedstocks.

MBI is a technology leader in fermentation-based succinic acid and has systematically derisked the production process by making improvements to the microbial strain, fermentation, and recovery steps. MBI isolated and patented a novel bacterium, Actinobacillus succinogenes, and has re-engineered its metabolism to increase productivity, improve yield, and reduce by-products. A. succinogenes is a particularly effective choice for clients seeking to use cellulosic sugars for the production of succinic acid as it simultaneously utilizes both 5 and 6 carbon sugars.

MBI is actively seeking to license or sell its patents for its biobased succinic acid platform.

AFEX Technology Platform

For every ton of corn, wheat and rice harvested today, an equal amount of crop residue is left behind. Nature locks away sugar sources in these residues, making them inaccessible. As the world faces rapidly increasing demands for sustainable food and fuels—by 2050, the planet will have to support 9 billion people—the ability to access these untapped sugar sources becomes all the more urgent.

After decades of research, a world-renowned scientist at Michigan State University (MSU) discovered an ingenious way to liberate these sugars, transforming ordinary crop residues into sustainable renewable fuels and feed for beef and dairy cattle.

MBI is actively seeking to license or sell its patents for its biobased succinic acid platform.